Press Releases

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2016
Dec 2016 | Download as pdf

Soluble Therapeutics Acquired by CytoBioscience more

Nov 2016 | Download as pdf

Young Living Essential Oils Partners with TFS Sandalwood Farms more

Nov 2016 | Download as pdf

Beaufort Memorial Using Xenex Germ-Zapping Robot to Destroy Pathogens That Can Cause Hospital-Acquired Infections more

Nov 2016 | Download as pdf

DNAtrix to Present Clinical Data at the 21st Annual Meeting of the Society for Neuro-Oncology more

Nov 2016 | Download as pdf

Cartersville Medical Center Unveils Xenex Germ-Zapping Robot more

Nov 2016 | Download as pdf

DNAtrix enters into license agreement with University of Florida to develop new oncolytic virus platform more

Nov 2016 | Download as pdf

DNAtrix Licenses Myxoma Virus for New Immunotherapy Platform more

Nov 2016 | Download as pdf

Supportive Data for the Use of Santalis Pharmaceuticals’ East Indian Sandalwood Oil (EISO) for the Treatment of Psoriasis is Presented at International Conference more

Nov 2016 | Download as pdf

Santalis Pharmaceuticals Obtains FDA Allowance To Start A Phase 2 Clinical Study For The Treatment Of Mild To Moderate Atopic Dermatitis (AD) more

Nov 2016 | Download as pdf

DNAtrix Announces First Patients Treated in Phase 2 Trial with DNX-2401 and KEYTRUDA more

Oct 2016 | Download as pdf

Robotics: Germ-Zappers Are Saving Lives more

Oct 2016 | Download as pdf

DHR first in RGV with xenon UV disinfection systems more

Oct 2016 | Download as pdf

neoSurgical® Announces CE Mark Approval of the neoClose® Laparoscopic Port Closure Device more

Oct 2016 | Download as pdf

Germ-zapping robot named 'Gronk' helped kill MRSA at Mass. high school more

Oct 2016 | Download as pdf

Doctors Hospital at Renaissance is First in Rio Grande Valley to Deploy Xenex Germ-Zapping Robots more

Oct 2016 | Download as pdf

Bio2 Medical's Angel Catheter successfully placed in first two patients more

Oct 2016 | Download as pdf

Cardiovate Develops First Bioabsorbable Vascular Graft more

Oct 2016 | Download as pdf

Funding San Antonio’s Biotech Ecosystem more

Oct 2016 | Download as pdf

A biotech groups to share in major military contract to manufacture stem cells more

Sept 2016 | Download as pdf

Robot disinfecting rooms at Life Line Hospital in Wintersville more

Sept 2016 | Download as pdf

Life Line Hospital is the First Long Term Acute Care Hospital in Ohio to Enhance Patient Safety by Deploying a Xenex Germ-Zapping Robot more

Sept 2016 | Download as pdf

Robots show Marin, Sonoma hospitals the light on disinfection more

Sept 2016 | Download as pdf

Santalis Pharmaceuticals Announces Issuance of Patent for the Use of Sandalwood Oil to Treat Cancers more

Sept 2016 | Download as pdf

Santalis Pharmaceuticals Initiates a Phase 2 Study of Mild, Moderate and Severe Atopic Dermatitis - Enrolls First Patient Into Its Australian Clinical Trial Site more

Sept 2016 | Download as pdf

With Scaffold for Regenerating Arteries, Cardiovate Raises $350,000

Xconomy Texas — San Antonio — An early stage San Antonio startup that aims to repair or replace clogged arteries with regenerated tissue has closed a small financing round from angel investors, The University of Texas Horizon Fund, and Targeted Technology, according to its CEO.

Cardiovate, founded in 2012, closed a $350,000 round of convertible notes from the investors in August, according to CEO Mark Standeford, who joined Cardiovate in 2014. The company plans to use that money, as well as an additional $150,000 it may seek, for patent legal work and to start a year-long animal study of its medical device, Standeford says.

The device is a type of bioabsorbable material called polycaprolactone (PCL), which are commonly used in tissue engineering or repair. Cardiovate’s PCL is a cylindrical scaffold is intended for people who suffer from peripheral arterial disease—blockages in blood vessels that carry blood from the heart to the body’s extremities, like the legs.

The condition impacts some 8.5 million Americans and predominately older individuals,according to the Centers for Disease Control. It blocks the flow of blood in the artery and can result in anything from severe pain to nerve damage to the loss of a limb, as well as high blood pressure and potential cardiac diseases, Standeford says.

The most common first treatment is to bypass the clog in the artery with another blood vessel from a patient or a cadaver, typically a vein since they’re more abundant. If that isn’t possible—it isn’t for about half of the patient population, Standeford says—physicians will look to restore blood flow with angioplasty. The physician in essence opens up the blocked artery with a balloon, and places a small mesh tube there (a stent) to keep blood flowing.

Using another blood vessel is generally preferable to a synthetic stent because the body’s immune system can react against the foreign material, and the clog can reform in the stent, Standeford says.
Cardiovate’s scaffold aims to act more like another blood vessel, and would be implanted similarly. The scaffold also bypasses the clog, connecting on either end of the artery. Its circular shape allows blood to flow through it, and as the blood does, the scaffold’s design helps regenerate new artery tissue, according to Standeford.

The inside of the scaffold has curved fibers, which help generate new endothelial lining for the artery—the tissue on the interior of a blood vessel—as the blood flows through the scaffold, he says. Meanwhile, the exterior of the scaffold has linear fibers, which Standeford says encourage the growth of smooth muscle cells that encourage growth of the exterior of the arteries. Once the artery has regenerated, the PCL scaffold gradually dissolves.

The company has had success in a very early, small 30-day trial, Standeford said, which was funded by a $150,000 SBIR grant from the National Science Foundation. Cardiovate hasn’t released the results yet. Standeford says the goal was to prove the scaffold could be not only better than synthetic products, but as good or better than harvested blood vessels.

“We’re going head-to-head with vein vascular bypass with the hopes that we would actually show some superiority because we’re actually developing arterial blood vessels,” Standeford says.
The company plans to apply for a second $750,000 grant from the NSF in January to help pay for its pending one-year animal study. It would be three to four years before the product could be considered for commercialization, he says.

The innovation and patentable part of the device—having circular or linear fibers to promote cellular growth—was developed by a University of Texas at San Antonio biomedical engineering student, Jordan Kaufmann, and her two advisors. Kaufmann is now the chief technical officer of Cardiovate. Her advisors, who are on the company’s board, were UTSA biomedical engineering professor Mauli Agrawal, and Steven Bailey, the chief of UT Health Science Center at San Antonio’s cardiology division.

Kaufmann won $50,000 from the UT Horizon Fund at a 2012 pitch competition.

Source: http://www.xconomy.com/ back

Aug 2016 | Download as pdf

Bluegrass Vascular Secures CE Mark Approval and Announces Successful Commercial Use of The Surfacer® Inside-Out® Access Catheter System more

Aug 2016 | Download as pdf

Bio2 Medical® Closes on $3 Million of Venture Debt Financing more

Aug 2016 | Download as pdf

Tropical Forestry Services prepares for first Indian sandalwood shipment to China more

Aug 2016 | Download as pdf

Bio2 Medical® Announces 510(k) Clearance from the FDA for the Angel® Catheter, the First Ever Prophylactic Use Indication for a Medical Device for Pulmonary Embolism more

Aug 2016 | Download as pdf

International perfumery competition winner tours Indian sandalwood plantations in the Kimberley more

Aug 2016 | Download as pdf

SA biotech firm drawing global interest year after moving from Germany more

Aug 2016 | Download as pdf

TFS Corporation makes bond offer more

Aug 2016 | Download as pdf

New robot system at USC Verdugo Hills Hospital uses UV light to disinfect hospital rooms more

Aug 2016 | Download as pdf

DNAtrix wins $2 million FDA grant for cancer immunotherapy more

Aug 2016 | Download as pdf

DNAtrix Awarded FDA Orphan Products Development Grant for DNX-2401 more

Aug 2016 | Download as pdf

TFS Corporation - July 2016 Update more

Aug 2016 | Download as pdf

StemBioSys reaches European distribution agreement for its products more

Aug 2016 | Download as pdf

BRIEF-Diamyd Medical: Cellaviva appointed European distributor for StemBioSys more

July 2016 | Download as pdf

DNAtrix Receives European Medicines Agency PRIME Designation more

July 2016 | Download as pdf

DNAtrix Announces Successful Intratumoral Delivery of DNX-2401 via Alcyone's MEMS Cannula for the Targeted Treatment of Recurrent Glioblastoma more

July 2016 | Download as pdf

Australia forestry company TFS Corp gets two ratings upgrades more

July 2016 | Download as pdf

Tour of Texas: Valence, Stellarray, Flux Farms, A&M, StemBioSys more

July 2016 | Download as pdf

StemBioSys reaches distribution agreement for its products in South Korea more

July 2016 | Download as pdf

Camden Clark Medical Center Introduces Newest Xenex Germ-Zapping Robot more

June 2016 | Download as pdf

MPR Client Innovative Trauma Care Wins Gold at 2016 Medical Design Excellence Awards more

June 2016 | Download as pdf

Santalis Pharmaceuticals Announces Positive Results From a Study Using 10% East Indian Sandalwood Oil (EISO) Serum Formulation for the Treatment of Mild-to-Moderate Plaque Psoriasis more

June 2016 | Download as pdf

Texas among top states in foreign investments more

June 2016 | Download as pdf

How Your Family Drives Business Decisions more

June 2016 | Download as pdf

StemBioSys enters distribution agreement for its products in Japan more

May 2016 | Download as pdf

San Antonio biotech firm takes big step toward global expansion more

May 2016 | Download as pdf

Vidant Edgecombe Hospital adds Xenex Germ-Zapping Robot to reduce HAIs more

May 2016 | Download as pdf

This hospital spent $300,000 on giant, superbug-killing robots more

May 2016 | Download as pdf

Santalis Announces First Subject Enrolled in Phase 2 Trial of East Indian Sandalwood Oil (EISO) to Treat Mild to Moderate Plaque Psoriasis more

May 2016 | Download as pdf

SA biotech company backing fed stem cell bill to cut red tape from regulatory pathway more

May 2016 | Download as pdf

Bexar County added 4,350 jobs last year, study says more

April 2016 | Download as pdf

Springfield Clinic unveils Xenex Germ-Zapping Robot for infection control more

April 2016 | Download as pdf

San Antonio venture capital funding fell last year more

April 2016 | Download as pdf

neoSurgical Limited Expands Indications For neoClose Device more

April 2016 | Download as pdf

Bio2 Medical Closes Series D Preferred Stock more

April 2016 | Download as pdf

TFS undertakes $60 million placement more

April 2016 | Download as pdf

Bluegrass Vascular Technologies’ catheter system used on first patient more

March 2016 | Download as pdf

Cytocentrics refunds $100,000 in economic development funds to city more

March 2016 | Download as pdf

Bluegrass Vascular Technologies Announces First Clinical Use of the Surfacer® Inside-Out® Access Catheter System in Europe. more

March 2016 | Download as pdf

Long-term acute care facility in California implements Xenex germ-zapping robot more

March 2016 | Download as pdf

Robotic housekeeper disinfects the rooms at Modesto hospital more

March 2016 | Download as pdf

Aerin Medical raises $16.7M, adds new board members more

March 2016 | Download as pdf

Brokers Sniff Sweet Potential In TFS Corp more

March 2016 | Download as pdf

East Indian sandalwood oil (EISO) is the key ingredient in these grooming products for dogs more

Feb 2016 | Download as pdf

Santalis Pharmaceuticals Completes the Spin-Off of Roxy’s Remedies Inc. more

Feb 2016 | Download as pdf

TFS Corporation - January 2016 Update more

Feb 2016 | Download as pdf

DNAtrix's Oncolytic Immunotherapy, DNX-2401, Awarded EU Orphan Medicine Designation more

Feb 2016 | Download as pdf

Strategic partnering deal with Cytocentrics more

Feb 2016 | Download as pdf

Cytocentrics CEO: San Antonio to get big boost from new deal more

Feb 2016 | Download as pdf

GhostBuster the Lab Mix Reviews Roxy’s Remedies Pure Relief Spray Gel more

Feb 2016 | Download as pdf

Avera McKennan Addresses Patient Safety with Germ-Zapping Robots more

Feb 2016 | Download as pdf

Santalis Pharmaceuticals Announces Positive Results from a Study of Pediatric Patients with Eczema more

Feb 2016 | Download as pdf

Santalis announces positive results for pediatric atopic dermatitis treatment more

Feb 2016 | Download as pdf

Here’s why the TFS Corporation Limited share price soared 28% today more

Jan 2016 | Download as pdf

Cytocentrics gaining traction in San Antonio more

Jan 2016 | Download as pdf

The Drugstore Acne Fighters Dermatologists Swear By more

Jan 2016 | Download as pdf

neoSurgical® Begins Postmarket Surveillance Study more

Jan 2016 | Download as pdf

Santalis Announces First Subject Enrolled in Phase 2 Trial more

Jan 2016 | Download as pdf

BiO2 Medical Reports Positive Advancement of the Series D Round of Funding more

Jan 2016 | Download as pdf

Germany’s Axiogenesis to collaborate with new San Antonio biotech company more